In-Clinic Use of Cantharidin for the Treatment of Molluscum Contagiosum

In-Clinic Use of Cantharidin for the Treatment of Molluscum Contagiosum - A Snapshot

- Cantharidin is a topical vesicant agent derived from blister beetles, used in dermatology for the treatment of molluscum contagiosum, a common viral skin infection primarily affecting children.

- Cantharidin induces blister formation by causing acantholysis, leading to the separation of epidermal cells and subsequent blistering and resolution of molluscum lesions.

- Cantharidin is available commercially in several countries outside of Australia, including the United States and Canada. It is marketed under the names Cantharone and Cantharone Plus. It requires compounding in Australia.

- Cantharone is applied in-clinic by doctors or nurses using a fine applicator, such as a toothpick or the wooden end of a cotton swab, to carefully target the molluscum lesions ensuring the liquid is not spread beyond 2mm of surrounding normal skin. The treated area can then be covered with tape or a bandage to prevent accidental spreading.

- Cantharone is highly effective in treating molluscum contagiosum, often clearing lesions with one or two treatments. Blisters form within 24 hours, and lesions typically resolve within 1-2 weeks.

- Mild pain, blistering, erythema, and temporary skin discoloration at the application site can be expected.

- It should be used carefuly in young children and avoided in patients with a history of severe reactions to cantharidin. It should not be used on mucosal sites or genitals and should be avoided in facial lesions.

- After the in-clinic application, patients are advised to keep the treated area dry and covered as directed. Any blistering or discomfort is typically managed with over-the-counter pain relief, but is usually minimal if any. Lesions should not be picked at to avoid scarring.

- Patients are usually scheduled for a follow-up visit in 1-2 weeks to assess the response to treatment and determine if additional applications as necessary.

- Cantharone provides a safe and effective in-clinic treatment for molluscum contagiosum, with minimal side effects when applied by trained healthcare professionals. Its use helps in achieving rapid resolution of lesions, improving patient comfort and satisfaction.